Post Exposure Prophylaxis

 
Anthrax
Ciprofloxacin 500mg PO q12h for 60 days
Doxycycline 100mg PO q12h for 60 days
Vaccine PPT Presentation Anthrax Vaccine
Botulism No PEP available
Plague
Doxycycline 100mg PO q12h for 7 days
Smallpox Vaccination within 4 days of exposure
Tularemia
  • Persons beginning treatment with streptomycin, gentamicin, doxycycline, or ciprofloxacin in the incubation period of tularemia and continuing treatment daily for 14 days might be protected against symptomatic infection. Therefore, if an attack is discovered before individuals become ill, exposed persons should be prophylactically treated with 14 days of oral doxycycline or ciprofloxacin.
  • If an attack is discovered only after individuals become ill, persons potentially exposed should begin a fever watch. Those who develop an otherwise unexplained fever or flu-like illness within 14 days of presumed exposure should begin treatment as outlined above.
  • Postexposure prophylactic treatment of close contacts of tularemia patients is not recommended because person-to-person transmission is not known to occur.
Doxycycline 100mg PO q12h for 14 days
Ciprofloxacin 500mg PO q12h for 14 days
Viral Hemorrhagic fevers No PEP available for most VHF. PEP for Lassa Fever: ribavirin used with some protective effects in case contacts. Yellow Fever vaccine not effective after BT event.
 

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